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Cellosaurus PSC-THP1-EP (CVCL_W367)

[Text version]

Cell line name PSC-THP1-EP
Accession CVCL_W367
Resource Identification Initiative To cite this cell line use: PSC-THP1-EP (RRID:CVCL_W367)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 06005.
Population: Japanese.
Derived from sampling site: Peripheral blood.
Sequence variations Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IR08 (PSC-THP1)
Children:
CVCL_W368 (PSC-THP1-EP-FAST)CVCL_W369 (PSC-THP1-EPEP)CVCL_W370 (PSC-THP1-HEP)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
Publications

Patent=US20110045519
Gennero L., Ponzetto A., Pescarmona G., Savarino A., Merizzi G.
Differentiated immortalised cell lines capable of producing albumin and blood coagulation factors, methods of preparing thereof from a leukaemia cell line and uses thereof.
Patent number US20110045519, 24-Feb-2011

Cross-references
Encyclopedic resources Wikidata; Q54948459
Entry history
Entry creation16-Apr-2014
Last entry update23-Sep-2021
Version number14