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Cellosaurus PSC-THP1-EP (CVCL_W367)

[Text version]

Cell line name PSC-THP1-EP
Accession CVCL_W367
Resource Identification Initiative To cite this cell line use: PSC-THP1-EP (RRID:CVCL_W367)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Advanced Biotechnology Center (ABC), Interlab Cell Line Collection (ICLC), Italy; PD 06005.
Population: Japanese.
Derived from sampling site: Peripheral blood.
Sequence variations Gene fusion; HGNC; 2457; CSNK2A1 + HGNC; 13917; DDX39B; Name(s)=CSNK2A1-DDX39B (from parent cell line).
Gene fusion; HGNC; 7132; KMT2A + HGNC; 7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg174fs*3 (c.520_545del26); Zygosity=Heterozygous (from parent cell line).
Disease Childhood acute monocytic leukemia (NCIt: C9163)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_IR08 (PSC-THP1)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line

Gennero L., Ponzetto A., Pescarmona G., Savarino A., Merizzi G.
Differentiated immortalised cell lines capable of producing albumin and blood coagulation factors, methods of preparing thereof from a leukaemia cell line and uses thereof.
Patent number US20110045519, 24-Feb-2011

Encyclopedic resources Wikidata; Q54948459
Entry history
Entry creation16-Apr-2014
Last entry update23-Sep-2021
Version number14