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Cellosaurus C-HC-4 (CVCL_W519)

[Text version]
Cell line name C-HC-4
Synonyms c-Hc-4; C-Hc4; cHc4; CHC4; HC-4; Hc-4
Accession CVCL_W519
Resource Identification Initiative To cite this cell line use: C-HC-4 (RRID:CVCL_W519)
Comments Population: Japanese.
Doubling time: ~20 hours (PubMed=2856442).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): TKG

Markers:
AmelogeninX
CSF1PO13
D5S81810
D7S82010,12
D13S31711
D16S5399
TH016,9
TPOX9
vWA14,18

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Publications

PubMed=6300668; DOI=10.1016/0027-5107(83)90097-0
Abe S., Nemoto N., Sasaki M.
Sister-chromatid exchange induction by indirect mutagens/carcinogens, aryl hydrocarbon hydroxylase activity and benzo[alpha]pyrene metabolism in cultured human hepatoma cells.
Mutat. Res. 109:83-90(1983)

PubMed=2856442
Sasaki F., Kameda H., Hata Y., Uchino J.
Establishment of the human hepatocellular carcinoma cell line and its characteristics.
Hum. Cell 1:89-91(1988)

PubMed=2543326
Hata Y., Igarashi M., Takada N., Namieno T., Sasaki F., Une Y., Uchino J., Kajiwara M.
Development of a new therapeutic method in hepatocellular carcinoma using a culture system -- the intensifying effect of human epidermal growth factor (hEGF) on the antitumor action of antitumor agents.
Gan To Kagaku Ryoho 16:1874-1879(1989)

PubMed=7874267; DOI=10.1007/BF02349278
Ikuta S., Itoh F., Hinoda Y., Toyota M., Makiguchi Y., Imai K., Yachi A.
Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma.
J. Gastroenterol. 29:727-732(1994)

PubMed=12029633; DOI=10.1053/jhep.2002.33683
Yasui K., Arii S., Zhao C., Imoto I., Ueda M., Nagai H., Emi M., Inazawa J.
TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas.
Hepatology 35:1476-1484(2002)

Cross-references
Cell line collections (Providers) TKG; TKG 0733
Cell line databases/resources CGH-DB; 9073-4
Chemistry resources ChEMBL-Cells; CHEMBL4523518
ChEMBL-Targets; CHEMBL4523549
PubChem_Cell_line; CVCL_W519
Encyclopedic resources Wikidata; Q54799760
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number12