ID   REPC
AC   CVCL_W815
SY   Renal EPO-Producing Cells
DR   BioSample; SAMN03151768
DR   Wikidata; Q54949755
RX   DOI=10.1182/blood-2014-04-571752;
RX   PubMed=21406725;
WW   https://retractionwatch.com/2014/04/29/contaminated-cells-force-retraction-of-blood-paper/
WW   http://iclac.org/wp-content/uploads/Cross-Contaminations_v10_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a Hep 3B2.1-7 derivative. Original paper (PubMed=21406725) has been retracted.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00487.
CC   Population: African American.
CC   Karyotypic information: Has lost chromosome Y.
CC   Sequence variation: Mutation; HGNC; 903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
CC   Caution: 10.1182/blood-2014-04-571752 is a retractation of PubMed=21406725.
DI   NCIt; C7955; Childhood hepatocellular carcinoma
DI   ORDO; Orphanet_33402; Pediatric hepatocellular carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0326 ! Hep 3B2.1-7
SX   Male
AG   8Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 20-05-21; Version: 16
//
RX   DOI=10.1182/blood-2014-04-571752;
RA   Frede S., Freitag P., Geuting L., Konietzny R., Fandrey J.;
RT   "Retraction.";
RL   Blood 123:3365-3365(2014).
//
RX   PubMed=21406725; DOI=10.1182/blood-2010-07-298083;
RA   Frede S., Freitag P., Geuting L., Konietzny R., Fandrey J.;
RT   "Oxygen-regulated expression of the erythropoietin gene in the human
RT   renal cell line REPC.";
RL   Blood 117:4905-4914(2011).
//