Cellosaurus cell line MCF-7/AZ (CVCL_W971)

• Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  
• Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
  

PubMed=1648947; DOI=10.1038/bjc.1991.191
Bracke M.E., Van Larebeke N.A., Vyncke B.M., Mareel M.M.
Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro.
Br. J. Cancer 63:867-872(1991)

PubMed=8528519; DOI=10.1007/BF02634317
Deman J.J., Van Larebeke N.A., Bruyneel E.A., Bracke M.E., Vermeulen S.J., Vennekens K.M., Mareel M.M.
Removal of sialic acid from the surface of human MCF-7 mammary cancer cells abolishes E-cadherin-dependent cell-cell adhesion in an aggregation assay.
In Vitro Cell. Dev. Biol. Anim. 31:633-639(1995)

PubMed=22161839; DOI=10.1387/ijdb.113336ld
Derycke L., Stove C., Vercoutter-Edouart A.-S., De Wever O., Dolle L., Colpaert N., Depypere H., Michalski J.-C., Bracke M.E.
The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells.
Int. J. Dev. Biol. 55:835-840(2011)