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Cellosaurus MCF-7/6 (CVCL_W972)

[Text version]

Cell line name MCF-7/6
Synonyms MCF-7-6
Accession CVCL_W972
Resource Identification Initiative To cite this cell line use: MCF-7/6 (RRID:CVCL_W972)
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for PIK3CA p.Glu545Lys (c.1633G>A) (ClinVar=VCV000013655) (from parent cell line).
Disease Invasive ductal carcinoma, not otherwise specified (NCIt: C4194)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line

PubMed=1648947; DOI=10.1038/bjc.1991.191
Bracke M.E., Van Larebeke N.A., Vyncke B.M., Mareel M.M.
Retinoic acid modulates both invasion and plasma membrane ruffling of MCF-7 human mammary carcinoma cells in vitro.
Br. J. Cancer 63:867-872(1991)

PubMed=8528519; DOI=10.1007/BF02634317
Deman J.J., Van Larebeke N.A., Bruyneel E.A., Bracke M.E., Vermeulen S.J., Vennekens K.M., Mareel M.M.
Removal of sialic acid from the surface of human MCF-7 mammary cancer cells abolishes E-cadherin-dependent cell-cell adhesion in an aggregation assay.
In Vitro Cell. Dev. Biol. Anim. 31:633-639(1995)

PubMed=22161839; DOI=10.1387/ijdb.113336ld
Derycke L., Stove C., Vercoutter-Edouart A.S., De Wever O., Dolle L., Colpaert N., Depypere H., Michalski J.C., Bracke M.
The role of non-muscle myosin IIA in aggregation and invasion of human MCF-7 breast cancer cells.
Int. J. Dev. Biol. 55:835-840(2011)

Other Wikidata; Q54904350
Polymorphism and mutation databases Cosmic; 2036670
Entry history
Entry creation17-Jul-2014
Last entry update02-Jul-2020
Version number9