Cell line name | HD10.6 | ||||||||||||||||||
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Accession | CVCL_WG82 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: HD10.6 (RRID:CVCL_WG82) | ||||||||||||||||||
Comments | Characteristics: Immortalized dorsal root ganglion (DRG) cell line that in the presence of doxycycline can differentiate into sensory neurons with nociceptive features (PubMed=10377351). Virology: Susceptible to infection by herpes simplex virus 1 (HHV-1). A quiescent state resembling latency can be established in the HSV-1 infection in the presence of acyclovir (PubMed=28404842). Doubling time: 1.2 days (PubMed=10377351). Transfected with: UniProtKB; P01110; Avian myelocytomatosis virus MC29 v-Myc. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transformant: v-Myc [Note=Tetracycline-regulated]. Miscellaneous: STR profile from personal communication of Triezenberg S.J. Derived from site: In situ; Dorsal root ganglion; UBERON=UBERON_0000044. Cell type: Neuron; CL=CL_0000540. | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||
Age at sampling | <12FW | ||||||||||||||||||
Category | Transformed cell line | ||||||||||||||||||
STR profile | Source(s): Direct_author_submission Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=10377351; DOI=10.1523/JNEUROSCI.19-13-05420.1999 CLPUB00486 PubMed=28404842; DOI=10.1128/JVI.00080-17 PubMed=32636736; DOI=10.3389/fncel.2020.00184 PubMed=35890047; DOI=10.3390/pathogens11070803 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Encyclopedic resources | Wikidata; Q93986083 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 24-May-2019 | ||||||||||||||||||
Last entry update | 05-Oct-2023 | ||||||||||||||||||
Version number | 8 |