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Cellosaurus K562/DAC (CVCL_WI19)

[Text version]

Cell line name K562/DAC
Accession CVCL_WI19
Resource Identification Initiative To cite this cell line use: K562/DAC (RRID:CVCL_WI19)
Comments Selected for resistance to: ChEBI; CHEBI:50131; 5-aza-2'-deoxycytidine (Decitabine).
Omics: Deep RNAseq analysis.
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line

PubMed=30793488; DOI=10.1111/jcmm.14221
Wen X.-M., Zhang T.-J., Ma J.-C., Zhou J.-D., Xu Z.-J., Zhu X.-W., Yuan Q., Ji R.-B., Chen Q., Deng Z.-Q., Lin J., Qian J.
Establishment and molecular characterization of decitabine-resistant K562 cells.
J. Cell. Mol. Med. 23:3317-3324(2019)

Other Wikidata; Q94335820
Entry history
Entry creation24-May-2019
Last entry update02-Jul-2020
Version number4