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Cellosaurus MG63.3 (CVCL_WL01)

[Text version]

Cell line name MG63.3
Accession CVCL_WL01
Resource Identification Initiative To cite this cell line use: MG63.3 (RRID:CVCL_WL01)
Comments Characteristics: Has a high metastatic potential.
Omics: Deep RNAseq analysis.
Omics: H3K4me1 ChIP-seq epigenome analysis.
Omics: H3K27ac ChIP-seq epigenome analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_R705 (MG63.2)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line

PubMed=26320182; DOI=10.18632/oncotarget.5177
Ren L., Mendoza A., Zhu J., Briggs J.W., Halsey C., Hong E.S., Burkett S.S., Morrow J., Lizardo M.M., Osborne T., Li S.Q., Luu H.H., Meltzer P.S., Khanna C.
Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.
Oncotarget 6:29469-29481(2015)

PubMed=29334376; DOI=10.1038/nm.4475
Morrow J.J., Bayles I., Funnell A.P.W., Miller T.E., Saiakhova A., Lizardo M.M., Bartels C.F., Kapteijn M.Y., Hung S., Mendoza A., Dhillon G., Chee D.R., Myers J.T., Allen F., Gambarotti M., Righi A., DiFeo A., Rubin B.P., Huang A.Y., Meltzer P.S., Helman L.J., Picci P., Versteeg H.H., Stamatoyannopoulos J.A., Khanna C., Scacheri P.C.
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.
Nat. Med. 24:176-185(2018)

Gene expression databases GEO; GSM1915000
GEO; GSM1915001
GEO; GSM1915002
GEO; GSM1915003
GEO; GSM1915030
GEO; GSM1915031
GEO; GSM1915032
GEO; GSM2635313
GEO; GSM2635314
Other Wikidata; Q95989262
Entry history
Entry creation24-May-2019
Last entry update02-Jul-2020
Version number3