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Cellosaurus NCI-H82-A (CVCL_WM70)

[Text version]
Cell line name NCI-H82-A
Synonyms NCI-H82A
Accession CVCL_WM70
Resource Identification Initiative To cite this cell line use: NCI-H82-A (RRID:CVCL_WM70)
Comments Population: Caucasian.
Characteristics: Established from parent cell line by selection of the adherent cells.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; 7577; MYH7 + HGNC; 9709; PVT1; Name(s)=PVT1-MYH7 (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Thr125Thr (c.375G>T); ClinVar=VCV000237948; Zygosity=Unspecified; Note=Impairs TP53 splicing dramatically (from parent cell line).
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1591 (NCI-H82)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
Publications

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H., Carney D.N., Vooijs G.P., Ramaekers F.C.S.
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=7720728
Senden N.H.M., van de Velde H.J.K., Broers J.L.V., Timmer E.D.J., Kuijpers H.J.H., Roebroek A.J.M., Van de Ven W.J.M., Ramaekers F.C.S.
Subcellular localization and supramolecular organization of neuroendocrine-specific protein B (NSP-B) in small cell lung cancer.
Eur. J. Cell Biol. 65:341-353(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM70
Encyclopedic resources Wikidata; Q95993676
Entry history
Entry creation24-May-2019
Last entry update05-Oct-2023
Version number10