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Cellosaurus OSE-MG63 (CVCL_WR53)

[Text version]
Cell line name OSE-MG63
Accession CVCL_WR53
Resource Identification Initiative To cite this cell line use: OSE-MG63 (RRID:CVCL_WR53)
Comments Population: Caucasian.
Characteristics: Transfected with a construct containing 6 tandem repeats of the osteoblastic specific element 2 (OSE2) and a minimal mOG2 promoter upstream of eGFP.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: Metastatic; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0426 (MG-63)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=23675497; DOI=10.1371/journal.pone.0063661
Dai Z.-Q., Wu F., Chen J., Xu H.-J., Wang H.-H., Guo F.-M., Tan Y.-J., Ding B., Wang J.-F., Wan Y.-M., Li Y.-H.
Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity.
PLoS ONE 8:E63661-E63661(2013)

Cross-references
Encyclopedic resources Wikidata; Q98128381
Entry history
Entry creation05-Jul-2019
Last entry update29-Jun-2023
Version number7