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Cellosaurus OSE-MG63 (CVCL_WR53)

[Text version]

Cell line name OSE-MG63
Accession CVCL_WR53
Resource Identification Initiative To cite this cell line use: OSE-MG63 (RRID:CVCL_WR53)
Comments Characteristics: Transfected with a construct containing 6 tandem repeats of the osteoblastic specific element 2 (OSE2), and a minimal mOG2 promoter upstream of eGFP.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Sequence variations Homozygous for CDKN2A deletion (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0426 (MG-63)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line

PubMed=23675497; DOI=10.1371/journal.pone.0063661
Dai Z.-Q., Wu F., Chen J., Xu H.-J., Wang H.-H., Guo F.-M., Tan Y.-J., Ding B., Wang J.-F., Wan Y.-M., Li Y.-H.
Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity.
PLoS ONE 8:E63661-E63661(2013)

Entry history
Entry creation05-Jul-2019
Last entry update12-Mar-2020
Version number2