| Cell line name | 5F11 |
|---|---|
| Accession | CVCL_WT46 |
| Resource Identification Initiative | To cite this cell line use: 5F11 (RRID:CVCL_WT46) |
| Comments | Biotechnology: The monoclonal antibody produced by this hybridoma was developed by Medarex into a therapeutic mAB known as Iratumumab (MDX-060) to be used in the treatment of oncological diseases such as relapsed refractory CD30-positive lymphoma including Hodgkin's disease. Monoclonal antibody isotype: IgG1, kappa. Monoclonal antibody target: UniProtKB; P28908; Human TNFRSF8/CD30. Miscellaneous: As the immunized splenic B-cells are from HuMAb mice the produced mAB is of human origin. |
| Species of origin | Mus musculus (Mouse) (NCBI Taxonomy: 10090) |
| Hierarchy | Parent: CVCL_4032 (P3X63Ag8.653) |
| Category | Hybridoma |
| Publications | PubMed=12881320; DOI=10.1182/blood-2003-02-0515 |
| Cross-references | |
| Biological sample resources | ABCD; ABCD_AD047 |
| Encyclopedic resources | Wikidata; Q93308285 |
| Entry history | |
| Entry creation | 05-Jul-2019 |
| Last entry update | 21-Mar-2023 |
| Version number | 5 |