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Cellosaurus SupT1.CCR5 (CVCL_WU88)

[Text version]

Cell line name SupT1.CCR5
Accession CVCL_WU88
Resource Identification Initiative To cite this cell line use: SupT1.CCR5 (RRID:CVCL_WU88)
Comments Transfected with: HGNC; 1606; CCR5.
Caution: There seems to be at least 3 different cell lines derived from Sup-T1 by transfection of human CCR5: Sup-T1-CCR5 (CVCL_X633), SupT1.CCR5 (CVCL_WU88) and SupT1-R5 (CVCL_WU89).
Derived from sampling site: Pleural effusion.
Sequence variations Heterozygous for EGFR p.Cys251Tyr (c.752G>A) (from parent cell line).
Heterozygous for KIT p.Arg177His (c.530G>A) (from parent cell line).
Heterozygous for MET p.Arg191Trp (c.571C>T) (from parent cell line).
Heterozygous for PIK3CA p.Glu545Asp (c.1635G>T) and p.Glu970Lys (c.2908G>A) (from parent cell line).
Heterozygous for PTCH1 p.Arg682Cys (c.2044C>T) (from parent cell line).
Heterozygous for SPRY4 p.Arg48Trp (c.142C>T) (from parent cell line).
Heterozygous for TP53 p.Arg267Leu (c.800G>T) (from parent cell line).
Disease Childhood T lymphoblastic lymphoma (NCIt: C7210)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1714 (SUP-T1)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
Publications

PubMed=15169555; DOI=10.1186/1742-4690-1-2
Princen K., Hatse S., Vermeire K., De Clercq E., Schols D.
Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists.
Retrovirology 1:2-2(2004)

Entry history
Entry creation05-Jul-2019
Last entry update05-Jul-2019
Version number1