Cell line name |
SupT1/Blam |
Synonyms |
SupT1/Beta-lactamase |
Accession |
CVCL_WV22 |
Resource Identification Initiative |
To cite this cell line use: SupT1/Blam (RRID:CVCL_WV22) |
Comments |
Population: Caucasian. Transfected with: HGNC; 1606; CCR5. Transfected with: UniProtKB; P62593; Escherichia coli beta-lactamase bla. Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
- Mutation; HGNC; 3236; EGFR; Simple; p.Cys251Tyr (c.752G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6342; KIT; Simple; p.Arg177His (c.530G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7029; MET; Simple; p.Arg191Trp (c.571C>T); ClinVar=VCV000568557; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Asp (c.1635G>T); ClinVar=VCV000217293; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu970Lys (c.2908G>A); ClinVar=VCV001057635; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9585; PTCH1; Simple; p.Arg682Cys (c.2044C>T); ClinVar=VCV000237466; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 15533; SPRY4; Simple; p.Arg25Trp (c.73C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg267Leu (c.800G>T); ClinVar=VCV000852206; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Childhood T lymphoblastic lymphoma (NCIt: C7210) T-cell non-Hodgkin lymphoma (ORDO: Orphanet_171918) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1714 (SUP-T1) Children:
|
Sex of cell |
Male |
Age at sampling |
8Y |
Category |
Cancer cell line |
Publications | PubMed=11884576; DOI=10.1128/jvi.76.7.3522-3533.2002 Lineberger J.E., Danzeisen R., Hazuda D.J., Simon A.J., Miller M.D. Altering expression levels of human immunodeficiency virus type 1 gp120-gp41 affects efficiency but not kinetics of cell-cell fusion. J. Virol. 76:3522-3533(2002) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_WV22
|
Encyclopedic resources |
Wikidata; Q98132880
|
Entry history |
Entry creation | 05-Jul-2019 |
Last entry update | 05-Oct-2023 |
Version number | 10 |
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