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Cellosaurus LAPC4-SL (CVCL_WZ26)

[Text version]
Cell line name LAPC4-SL
Synonyms Stem-Like LAPC4; LAPC4-Stem Like
Accession CVCL_WZ26
Resource Identification Initiative To cite this cell line use: LAPC4-SL (RRID:CVCL_WZ26)
Comments Characteristics: Reprogrammed to, maintained and propagated as cancer stem-like cells (CSCs) by growth in androgen-free neural/neural crest (N/NC) stem medium.
Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4744 (LAPC-4)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=28145883; DOI=10.18632/oncotarget.14850
Nouri M., Caradec J., Lubik A.A., Li N., Hollier B.G., Takhar M., Altimirano-Dimas M., Chen M.-Q., Roshan-Moniri M., Butler M., Lehman M., Bishop J., Truong S., Huang S.-C., Cochrane D., Cox M., Collins C., Gleave M.E., Erho N., Alshalafa M., Davicioni E., Nelson C., Gregory-Evans S., Karnes R.J., Jenkins R.B., Klein E.A., Buttyan R.
Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance.
Oncotarget 8:18949-18967(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WZ26
Encyclopedic resources Wikidata; Q95981289
Gene expression databases GEO; GSM1633308
GEO; GSM1633309
GEO; GSM1633310
Entry history
Entry creation06-Sep-2019
Last entry update05-Oct-2023
Version number8