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Cellosaurus U-937-AG (CVCL_X000)

[Text version]

Cell line name U-937-AG
Synonyms U-937 AG
Accession CVCL_X000
Resource Identification Initiative To cite this cell line use: U-937-AG (RRID:CVCL_X000)
Comments Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line

PubMed=6748730; DOI=10.1016/0145-2126(84)90084-5
Peacock T.E., Kay N.E., Ascensao J.L., Kaplan M.E.
Establishment and characterization of a subclone (U-937-AG) from a permanent human monocyte cell line.
Leuk. Res. 8:435-439(1984)

Other Wikidata; Q54973608
Entry history
Entry creation17-Jul-2014
Last entry update02-Jul-2020
Version number7