ID   hTERT-EEC-B37
AC   CVCL_X007
SY   hTERT-EEC
DR   BioSample; SAMN03151839
DR   cancercelllines; CVCL_X007
DR   Wikidata; Q54896620
RX   DOI=10.1530/jme.1.01550e;
RX   PubMed=15821114;
RX   PubMed=22710073;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
CC   Problematic cell line: Contaminated. Shown to be a MCF-7 derivative (PubMed=22710073).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00462.
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 05-10-23; Version: 20
//
RX   DOI=10.1530/jme.1.01550e;
RA   Hombach-Klonisch S., Kehlen A., Fowler P.A., Huppertz B., Jugert J.F.,
RA   Bischoff G., Schluter E., Buchmann J., Klonisch T.;
RT   "Erratum to: regulation of functional steroid receptors and
RT   ligand-induced responses in telomerase-immortalized human endometrial
RT   epithelial cells.";
RL   J. Mol. Endocrinol. 51:X1-X1(2013).
//
RX   PubMed=15821114; DOI=10.1677/jme.1.01550;
RA   Hombach-Klonisch S., Kehlen A., Fowler P.A., Huppertz B., Jugert J.F.,
RA   Bischoff G., Schluter E., Buchmann J., Klonisch T.;
RT   "Regulation of functional steroid receptors and ligand-induced
RT   responses in telomerase-immortalized human endometrial epithelial
RT   cells.";
RL   J. Mol. Endocrinol. 34:517-534(2005).
//
RX   PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017;
RA   Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K.,
RA   Lessey B.A., Jordan V.C., Bradford A.P.;
RT   "DNA profiling analysis of endometrial and ovarian cell lines reveals
RT   misidentification, redundancy and contamination.";
RL   Gynecol. Oncol. 127:241-248(2012).
//