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Cellosaurus HEY C2 (CVCL_X009)

[Text version]
Cell line name HEY C2
Synonyms HEY-C2; Hey-C2; Hey C2; HEYC2; HeyC2
Accession CVCL_X009
Resource Identification Initiative To cite this cell line use: HEY C2 (RRID:CVCL_X009)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Glu (c.1391G>A); ClinVar=VCV000013964; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0297 (HEY)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22710073

Markers:
AmelogeninX
CSF1PO10,11
D2S133824,25
D3S135816
D5S81811,12
D7S82012
D8S117913
D13S31711
D16S5398,12
D18S5115
D19S43313,14
D21S1130
FGA20,21
TH018,9.3
TPOX11
vWA16,17

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_X009
Cell_Model_Passport; SIDM01216
Encyclopedic resources Wikidata; Q54883215
Gene expression databases GEO; GSM659378
GEO; GSM1340582
Entry history
Entry creation17-Jul-2014
Last entry update05-Oct-2023
Version number15