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Cellosaurus SCLC-16HC (CVCL_X025)

Cell line name SCLC-16HC
Synonyms SCLC-16H
Accession CVCL_X025
Resource Identification Initiative To cite this cell line use: SCLC-16HC (RRID:CVCL_X025)
Comments Problematic cell line: Contaminated. Shown to be a SCLC-21H (or SCLC-22H) derivative (PubMed=10508494; PubMed=20143388).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00158.
Population: Caucasian.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0024 (SCLC-21H)
Children:
CVCL_X026 (SCLC-16HV)
Sex of cell Male
Age at sampling 46Y
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx
Publications

PubMed=2438285; DOI=10.1007/BF00396382
Bepler G., Jaques G., Koehler A., Gropp C., Havemann K.
Markers and characteristics of human SCLC cell lines. Neuroendocrine markers, classical tumor markers, and chromosomal characteristics of permanent human small cell lung cancer cell lines.
J. Cancer Res. Clin. Oncol. 113:253-259(1987)

PubMed=2473086; DOI=10.1242/jcs.91.1.91
Broers J.L.V., Rot M.K., Oostendorp T., Bepler G., de Leij L.F.M.H., Carney D.N., Vooijs G.P., Ramaekers F.C.S.
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988)

PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Broers J.L.V., Mijnheere E.P., Rot M.K., Schaart G., Sijlmans A., Boerman O.C., Ramaekers F.C.S.
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991)

PubMed=1320893; DOI=10.1159/000163712
Verbeeck M.A.E., Elands J.P.M., de Leij L.F.M.H., Buys C.H.C.M., Carney D.N., Bepler G., Roebroek A.J.M., van de Ven W.J.M., Burbach J.P.H.
Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines.
Pathobiology 60:136-142(1992)

PubMed=10508494; DOI=10.1002/(SICI)1097-0215(19991112)83:4<555::AID-IJC19>3.0.CO;2-2
MacLeod R.A.F., Dirks W.G., Matsuo Y., Kaufmann M., Milch H., Drexler H.G.
Widespread intraspecies cross-contamination of human tumor cell lines arising at source.
Int. J. Cancer 83:555-563(1999)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151912
Encyclopedic resources Wikidata; Q54952441
Entry history
Entry creation17-Jul-2014
Last entry update29-Jun-2023
Version number16