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Cellosaurus SKMES-1-Taxol (CVCL_X336)

[Text version]

Cell line name SKMES-1-Taxol
Accession CVCL_X336
Resource Identification Initiative To cite this cell line use: SKMES-1-Taxol (RRID:CVCL_X336)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:45863; Paclitaxel (Taxol).
Omics: Proteome analysis.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Glu298Ter (c.892G>T); ClinVar=VCV000093323; Zygosity=Homozygous (from parent cell line).
Disease Lung squamous cell carcinoma (NCIt: C3493)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0630 (SK-MES-1)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
Publications

PubMed=18503785; DOI=10.1016/j.bbapap.2008.04.014
Murphy L., Henry M., Meleady P., Clynes M., Keenan J.
Proteomic investigation of taxol and taxotere resistance and invasiveness in a squamous lung carcinoma cell line.
Biochim. Biophys. Acta 1784:1184-1191(2008)

Cross-references
Encyclopedic resources Wikidata; Q54954751
Entry history
Entry creation17-Jul-2014
Last entry update23-Jun-2022
Version number12