ID   EMC-BAC-2
AC   CVCL_X487
SY   EMCBAC2
DR   ArrayExpress; E-MTAB-3610
DR   CCLE; EMCBAC2_LUNG
DR   Cell_Model_Passport; SIDM00047
DR   Cosmic-CLP; 1503370
DR   DepMap; ACH-002102
DR   GDSC; 1503370
DR   GEO; GSM1669764
DR   PharmacoDB; EMCBAC2_333_2019
DR   Wikidata; Q54832280
RX   PubMed=27397505;
RX   PubMed=30894373;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Part of: COSMIC cell lines project.
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Sequence variation: Homozygous for KRAS p.Gly12Ala (c.35G>C) (CCLE; Cosmic-CLP).
CC   Sequence variation: Homozygous for STK11 p.Gln37Ter (c.109C>T) (CCLE; Cosmic-CLP).
CC   Omics: Deep exome analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=0.13%; Native American=0%; East Asian, North=1.05%; East Asian, South=0%; South Asian=0%; European, North=72.26%; European, South=26.55% (PubMed=30894373).
ST   Source(s): Cosmic-CLP
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 11,12
ST   D16S539: 10,12
ST   D5S818: 11,13
ST   D7S820: 7,9
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 17
DI   NCIt; C2926; Non-small cell lung carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 06-09-19; Version: 12
//
RX   PubMed=27397505; DOI=10.1016/j.cell.2016.06.017;
RA   Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P.,
RA   Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H.,
RA   Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H.,
RA   Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X.,
RA   Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M.,
RA   Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M.,
RA   Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A.,
RA   Saez-Rodriguez J., McDermott U., Garnett M.J.;
RT   "A landscape of pharmacogenomic interactions in cancer.";
RL   Cell 166:740-754(2016).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//