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Cellosaurus NCC021 (CVCL_X506)

[Text version]

Cell line name NCC021
Accession CVCL_X506
Resource Identification Initiative To cite this cell line use: NCC021 (RRID:CVCL_X506)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.31
Native American0.02
East Asian, North27.12
East Asian, South71.39
South Asian1.05
European, North0
European, South0.12
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,13
D7S8209
D13S3178,9
D16S5399
TH019
TPOX8
vWA17,19

Run an STR similarity search on this cell line
Publications

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; NCC021_KIDNEY
Cell_Model_Passport; SIDM00232
Cosmic-CLP; 1509074
DepMap; ACH-002168
GDSC; 1509074
Chemistry resources PharmacoDB; NCC021_998_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670158
Other Wikidata; Q54907638
Entry history
Entry creation05-Sep-2014
Last entry updated06-Sep-2019
Version number13