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Cellosaurus PL18 [Human pancreatic adenocarcinoma] (CVCL_X507)

[Text version]

Cell line name PL18 [Human pancreatic adenocarcinoma]
Synonyms PL-18
Accession CVCL_X507
Resource Identification Initiative To cite this cell line use: PL18 [Human pancreatic adenocarcinoma] (RRID:CVCL_X507)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.21
East Asian, North72.33
East Asian, South25.99
South Asian0.14
European, North1.19
European, South0.14
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO10,12
D5S81810,12
D7S82010,11
D13S3178,11
D16S5399,13
TH017,9.3
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=29444439; DOI=10.1016/j.celrep.2018.01.051
Yuan T.L., Amzallag A., Bagni R., Yi M., Afghani S., Burgan W., Fer N., Strathern L.A., Powell K., Smith B., Waters A.M., Drubin D., Thomson T., Liao R., Greninger P., Stein G.T., Murchie E., Cortez E., Egan R.K., Procter L., Bess M., Cheng K.T., Lee C.-S., Lee L.C., Fellmann C., Stephens R., Luo J., Lowe S.W., Benes C.H., McCormick F.
Differential effector engagement by oncogenic KRAS.
Cell Rep. 22:1889-1902(2018)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; PL18_PANCREAS
Cell_Model_Passport; SIDM00054
Cosmic-CLP; 1240208
DepMap; ACH-002185
GDSC; 1240208
Chemistry resources PharmacoDB; PL18_1271_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670350
Other Wikidata; Q54947496
Entry history
Entry creation05-Sep-2014
Last entry updated06-Sep-2019
Version number13