ID   HUT 78/SIVmac251
AC   CVCL_X609
SY   HUT-78-SIVmac251
DR   cancercelllines; CVCL_X609
DR   HIVReagentProgram; ARP-160
DR   Wikidata; Q54896915
RX   PubMed=3159089;
CC   Population: Caucasian.
CC   Virology: Infected with simian immunodeficiency virus isolate SIVmac251 (HIVReagentProgram=ARP-160).
CC   Sequence variation: Gene deletion; HGNC; 7208; MPDZ; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3366; Sezary syndrome
DI   ORDO; Orphanet_3162; Sezary syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0337 ! HuT 78
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 05-10-23; Version: 14
//
RX   PubMed=3159089; DOI=10.1126/science.3159089;
RA   Daniel M.D., Letvin N.L., King N.W. Jr., Kannagi M., Sehgal P.K.,
RA   Hunt R.D., Kanki P.J., Essex M., Desrosiers R.C.;
RT   "Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.";
RL   Science 228:1201-1204(1985).
//