Cell line name |
Sup-T1-CCR5 |
Synonyms |
SupT1/CCR5; SupT1-CCR5 |
Accession |
CVCL_X633 |
Resource Identification Initiative |
To cite this cell line use: Sup-T1-CCR5 (RRID:CVCL_X633) |
Comments |
Population: Caucasian. Transfected with: HGNC; 1606; CCR5. Miscellaneous: STR profile from personal communication of Fernandez M. Caution: There seem to be at least 6 different cell lines derived from Sup-T1 by transfection of human CCR5: Sup-T1-CCR5 (Cellosaurus=CVCL_X633), SupT1.CCR5 (Cellosaurus=CVCL_WU88), SupT1-R5 (Cellosaurus=CVCL_WU89), Sup-T1 CCR5+ H6 (Cellosaurus=CVCL_A9NU), Sup-T1 CCR5+ L23 (Cellosaurus=CVCL_A9NV) and Sup-T1 CCR5+ M10 (Cellosaurus=CVCL_A9NW). Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175. Cell type: T-cell; CL=CL_0000084. |
Sequence variations |
- Mutation; HGNC; 3236; EGFR; Simple; p.Cys251Tyr (c.752G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 6342; KIT; Simple; p.Arg177His (c.530G>A); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7029; MET; Simple; p.Arg191Trp (c.571C>T); ClinVar=VCV000568557; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Asp (c.1635G>T); ClinVar=VCV000217293; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu970Lys (c.2908G>A); ClinVar=VCV001057635; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9585; PTCH1; Simple; p.Arg682Cys (c.2044C>T); ClinVar=VCV000237466; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 15533; SPRY4; Simple; p.Arg25Trp (c.73C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Arg267Leu (c.800G>T); ClinVar=VCV000852206; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Childhood T lymphoblastic lymphoma (NCIt: C7210) T-cell non-Hodgkin lymphoma (ORDO: Orphanet_171918) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_1714 (SUP-T1) |
Sex of cell |
Male |
Age at sampling |
8Y |
Category |
Cancer cell line |
STR profile |
Source(s): Direct_author_submission
Markers:Amelogenin | X,Y |
CSF1PO | 10,11,12 |
D3S1358 | 16,17,18,19,20 |
D5S818 | 11 |
D7S820 | 11 |
D8S1179 | 13,14 |
D13S317 | 11,12 |
D16S539 | 9,12,13 |
D18S51 | 13,14 |
D21S11 | 27,28,32,33 |
FGA | 19,20,21 |
Penta D | 12 |
Penta E | 14,16 |
TH01 | 9.3 |
TPOX | 9 |
vWA | 16,17,18,19 |
Run an STR similarity search on this cell line |
Publications | PubMed=11264379; DOI=10.1128/JVI.75.8.3903-3915.2001 Means R.E., Matthews T., Hoxie J.A., Malim M.H., Kodama T., Desrosiers R.C. Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4. J. Virol. 75:3903-3915(2001) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_X633
|
Encyclopedic resources |
Wikidata; Q54970881
|
Entry history |
Entry creation | 05-Sep-2014 |
Last entry update | 05-Oct-2023 |
Version number | 16 |
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