ID   HUT 78/HIV-2D205
AC   CVCL_X683
SY   HUT 78 HIV-2 D205-Infected
DR   cancercelllines; CVCL_X683
DR   Wikidata; Q54896912
RX   PubMed=2467304;
CC   Population: Caucasian.
CC   Virology: Infected with HIV-2 isolate D205.
CC   Sequence variation: Gene deletion; HGNC; 7208; MPDZ; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3366; Sezary syndrome
DI   ORDO; Orphanet_3162; Sezary syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0337 ! HuT 78
SX   Male
AG   53Y
CA   Cancer cell line
DT   Created: 05-09-14; Last updated: 05-10-23; Version: 14
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RX   PubMed=2467304; DOI=10.1073/pnas.86.7.2383;
RA   Kuhnel H., von Briesen H., Dietrich U., Adamski M., Mix D.,
RA   Biesert L., Kreutz R., Immelmann A., Henco K., Meichsner C.,
RA   Andreesen R., Gelderblom H., Rubsamen-Waigmann H.;
RT   "Molecular cloning of two West African human immunodeficiency virus
RT   type 2 isolates that replicate well in macrophages: a Gambian isolate,
RT   from a patient with neurologic acquired immunodeficiency syndrome, and
RT   a highly divergent Ghanian isolate.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:2383-2387(1989).
//