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Cellosaurus 1G5 (CVCL_X694)

[Text version]

Cell line name 1G5
Accession CVCL_X694
Resource Identification Initiative To cite this cell line use: 1G5 (RRID:CVCL_X694)
Comments Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for BAX p.Glu41Argfs*19 (c.121delG) (ClinVar=VCV000009512) (from parent cell line).
Heterozygous for BAX p.Glu41Glyfs*33 (c.121dupG) (ClinVar=VCV000009511) (from parent cell line).
Heterozygous for FBXW7 p.Arg505Cys (c.1513C>T) (ClinVar=VCV000069961) (from parent cell line).
Heterozygous for INPP5D p.Gln345Ter (c.1033C>T) (from parent cell line).
Heterozygous for INPP5D c.1097+1065_1097+1112del47 (from parent cell line).
Homozygous for MSH2 p.Arg711Ter (c.2131C>T) (ClinVar=VCV000090903) (from parent cell line).
Homozygous for MSH6 p.Phe1088Serfs*2 (c.3261delC) (ClinVar=VCV000089363) (from parent cell line).
Heterozygous for SYK p.Met34Hisfs*3 (c.98_99insG) (from parent cell line).
Heterozygous for TP53 p.Arg196Ter (c.586C>T) (ClinVar=VCV000043589) (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0367 (Jurkat E6.1)
Sex of cell Male
Age at sampling 14Y
Category Cancer cell line
Publications

PubMed=8018390; DOI=10.1089/aid.1994.10.295
Aguilar-Cordova E., Chinen J., Donehower L., Lewis D.E., Belmont J.W.
A sensitive reporter cell line for HIV-1 tat activity, HIV-1 inhibitors, and T cell activation effects.
AIDS Res. Hum. Retroviruses 10:295-301(1994)

Cross-references
Cell line collections NIH-ARP; 1819-249
Other Wikidata; Q54582896
Entry history
Entry creation05-Sep-2014
Last entry update12-Jan-2021
Version number11