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Cellosaurus HES-3 INSGFP/w (CVCL_XA15)

[Text version]
Cell line name HES-3 INSGFP/w
Synonyms HES3 INS(GFP/w); HES3 INSGFP/w; INSULIN(GFP/w) HES3
Accession CVCL_XA15
Resource Identification Initiative To cite this cell line use: HES-3 INSGFP/w (RRID:CVCL_XA15)
Comments Characteristics: Using homologous recombination an EGFP reporter gene was introduced in one allele of the INS locus (PubMed=22120512).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7158 (HES-3)
Children:
CVCL_C0CN (ESIBIe003-A-10)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=22120512; DOI=10.1007/s00125-011-2379-y
Micallef S.J., Li X., Schiesser J.V., Hirst C.E., Yu Q.C., Lim S.M., Nostro M.C., Elliott D.A., Sarangi F., Harrison L.C., Keller G., Elefanty A.G., Stanley E.G.
INS(GFP/w) human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells.
Diabetologia 55:694-706(2012)

Cross-references
Encyclopedic resources Wikidata; Q94104651
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number6