Cellosaurus logo
expasy logo

Cellosaurus H2030-TGL (CVCL_XA21)

[Text version]
Cell line name H2030-TGL
Accession CVCL_XA21
Resource Identification Initiative To cite this cell line use: H2030-TGL (RRID:CVCL_XA21)
Comments Population: Caucasian.
Characteristics: Transfected with HSV1-TK/GFP/Fluc (TGL).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Omics: Transcriptome analysis by microarray.
Caution: In PubMed=19576624 and the associated GEO data sets H2030-TGL is termed H2030 Parental.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Cys (c.34G>T); ClinVar=VCV000012578; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Gly262Val (c.785G>T); ClinVar=VCV000428889; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1517 (NCI-H2030)
Children:
CVCL_XA22 (H2030-BrM3)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=19576624; DOI=10.1016/j.cell.2009.04.030
Nguyen D.X., Chiang A.C., Zhang X.H.-F., Kim J.Y., Kris M.G., Ladanyi M., Gerald W.L., Massague J.
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis.
Cell 138:51-62(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_XA21
Encyclopedic resources Wikidata; Q93936092
Gene expression databases GEO; GSM354017
GEO; GSM354018
Entry history
Entry creation06-Sep-2019
Last entry update05-Oct-2023
Version number7