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Cellosaurus SK-OV-3-Cas9-564 (CVCL_XB86)

[Text version]

Cell line name SK-OV-3-Cas9-564
Accession CVCL_XB86
Resource Identification Initiative To cite this cell line use: SK-OV-3-Cas9-564 (RRID:CVCL_XB86)
Comments Characteristics: Transfected with a Cas9-Flag-Neo construct.
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Sequence variations Mutation; HGNC; 583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Leu (c.1514G>T); ClinVar=VCV000376424; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Ser90Profs*33 (c.267delC); ClinVar=VCV000156515; Zygosity=Homozygous (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Derived from metastatic site: Ascites.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0532 (SK-OV-3)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO11
D2S133818,23
D3S135814
D5S81810,11
D6S104312
D7S82013,14
D8S117914,15
D12S39122
D13S3178,11
D16S53912
D18S5116,17,18
D19S43314,14.2
D21S1130,31.2
FGA24,25
Penta E5,13
TH019,9.3
TPOX8,11
vWA17,18

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Cross-references
Cell line databases/resources CCRID; 1101HUM-PUMC000564
Other Wikidata; Q98132668
Entry history
Entry creation06-Sep-2019
Last entry update23-Sep-2021
Version number5