Home  |  Contact

Cellosaurus REGUi003-A (CVCL_XC58)

[Text version]
Cell line name REGUi003-A
Synonyms WRN iPSC; WERNER iPSC
Accession CVCL_XC58
Resource Identification Initiative To cite this cell line use: REGUi003-A (RRID:CVCL_XC58)
Comments From: Institute for Regenerative Medecine and Biotherapy; Montpellier; France.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; 12791; WRN; Simple; p.Tyr1263Ter (c.3789C>G); Zygosity=Homozygous (PubMed=31404747).
Disease Werner syndrome (NCIt: C3447)
Werner syndrome (ORDO: Orphanet_902)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=31404747

Markers:
AmelogeninX,Y
CSF1PO12
D3S135816,18
D5S81810,12
D7S8209
D8S117910,15
D13S31711,14
D16S53912,13
D18S5116,17
D21S1130,31
FGA21,23
Penta D11,14
Penta E5,13
TH017
TPOX8,9
vWA14,18

Run an STR similarity search on this cell line
Publications

CLPUB00552
Gatinois V.
Pathologies of helicases and premature aging: study by derivation of induced pluripotent stem cells.
Thesis PhD (2017), Universite de Montpellier, France

PubMed=31404747; DOI=10.1016/j.scr.2019.101515
Gatinois V., Desprat R., Becker F., Pichard L., Bernex F., Corsini C., Pellestor F., Lemaitre J.-M.
Reprogramming of human peripheral blood mononuclear cell (PBMC) from a patient suffering of a Werner syndrome resulting in iPSC line (REGUi003-A) maintaining a short telomere length.
Stem Cell Res. 39:101515-101515(2019)

Cross-references
Cell line databases/resources hPSCreg; REGUi003-A
Encyclopedic resources Wikidata; Q98128894
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number6