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Cellosaurus HEC-1-B-Cas9-587 (CVCL_XC91)

[Text version]
Cell line name HEC-1-B-Cas9-587
Accession CVCL_XC91
Resource Identification Initiative To cite this cell line use: HEC-1-B-Cas9-587 (RRID:CVCL_XC91)
Comments Population: Japanese.
Characteristics: Transfected with a Cas9-Flag-Neo construct.
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Endometrium; UBERON=UBERON_0001295.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7329; MSH6; Simple; c.4001+1G>T; ClinVar=VCV001736936; Zygosity=Heterozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 9122; PMS2; Simple; p.Arg802Ter (c.2404C>T); ClinVar=VCV000009237; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0294 (HEC-1-B)
Sex of cell Female
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO10,12
D2S133818,19
D3S135815
D5S81811,13
D6S104312,18
D7S8209,11
D8S117913,14
D12S39118,19
D13S31711
D16S53911,12
D18S5116,20
D19S43313
D21S1130,31
FGA21
Penta E11
TH016,7
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Cross-references
Cell line databases/resources cancercelllines; CVCL_XC91
CCRID; 1101HUM-PUMC000587
Encyclopedic resources Wikidata; Q94091563
Entry history
Entry creation06-Sep-2019
Last entry update05-Oct-2023
Version number9