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Cellosaurus KKK-D068 (CVCL_XD18)

[Text version]
Cell line name KKK-D068
Synonyms KKK-D068H1
Accession CVCL_XD18
Resource Identification Initiative To cite this cell line use: KKK-D068 (RRID:CVCL_XD18)
Comments Population: Southeast Asian; Thai.
Characteristics: Established from a first generation xenograft established in BALB/c Rag-2-/-/Jak3-/- mice.
Derived from site: In situ; Bile duct; UBERON=UBERON_0002394.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Opisthorchis viverrini-related cholangiocarcinoma (NCIt: C27769)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): JCRB; PubMed=31126020

Markers:
AmelogeninX
CSF1PO11
D2S133819
D3S135815
D5S81811,12
D7S8208,10
D8S117912,16
D13S3178,12
D16S5399
D18S5112
D19S43314,14.2
D21S1130,33.2
FGA23,25
TH017
TPOX8,11
vWA14,16

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Publications

PubMed=31077409; DOI=10.1002/hep.30704
Sittithumcharee G., Suppramote O., Vaeteewoottacharn K., Sirisuksakun C., Jamnongsong S., Laphanuwat P., Suntiparpluacha M., Matha A., Chusorn P., Buraphat P., Kakanaporn C., Charngkaew K., Silsirivanit A., Korphaisarn K., Limsrichamrern S., Tripatara P., Pairojkul C., Wongkham S., Sampattavanich S., Okada S., Jirawatnotai S.
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=31126020; DOI=10.3390/cells8050496
Vaeteewoottacharn K., Pairojkul C., Kariya R., Muisuk K., Imtawil K., Chamgramol Y., Bhudhisawasdi V., Khuntikeo N., Pugkhem A., Saeseow O.-T., Silsirivanit A., Wongkham C., Wongkham S., Okada S.
Establishment of highly transplantable cholangiocarcinoma cell lines from a patient-derived xenograft mouse model.
Cells 8:496.1-496.15(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1775
Encyclopedic resources Wikidata; Q94340046
Entry history
Entry creation06-Sep-2019
Last entry update29-Jun-2023
Version number7