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Cellosaurus K562-Wnt5a (CVCL_XE50)

[Text version]

Cell line name K562-Wnt5a
Accession CVCL_XE50
Resource Identification Initiative To cite this cell line use: K562-Wnt5a (RRID:CVCL_XE50)
Comments Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C200958.
Transfected with: HGNC; 12784; WNT5A.
Derived from sampling site: Pleural effusion.
Sequence variations BCR-ABL1 gene fusion (from parent cell line).
Homozygous for TP53 p.Gln136fs*13 (c.406_407insC) (from parent cell line).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=1814

Si W.-K., Li J., Li Z.-Q., Pan J., Niu C.-C., Zhao W.
Transgenic cell K562-Wnt5a and preparation method thereof.
Patent number CN101724603A, 09-Jun-2010

PubMed=21069266; DOI=10.3892/ijmm.2010.560
Yuan Y., Niu C.-C., Deng G., Li Z.-Q., Pan J., Zhao C., Yang Z.-L., Si W.-K.
The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells.
Int. J. Mol. Med. 27:63-69(2011)

Cell line databases/resources CCRID; 3142C0001000000713
Other Wikidata; Q94335728
Entry history
Entry creation06-Sep-2019
Last entry update02-Jul-2020
Version number3