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Cellosaurus Hep3b-Cas9-745 (CVCL_XE55)

[Text version]

Cell line name Hep3b-Cas9-745
Accession CVCL_XE55
Resource Identification Initiative To cite this cell line use: Hep3b-Cas9-745 (RRID:CVCL_XE55)
Comments Population: African American.
Characteristics: Transfected with a Cas9-Flag-Neo construct.
Karyotypic information: Has lost chromosome Y.
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Sequence variations Mutation; HGNC; 903; AXIN1; Simple; p.Arg146Ter (c.436C>T); Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
Disease Childhood hepatocellular carcinoma (NCIt: C7955)
Pediatric hepatocellular carcinoma (ORDO: Orphanet_33402)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0326 (Hep 3B2.1-7)
Sex of cell Male
Age at sampling 8Y
Category Cancer cell line
STR profile Source(s): CCRID

Markers:
AmelogeninX
CSF1PO8
D2S133821,25
D3S135815
D5S81813
D6S104312,17
D7S8208
D8S117912
D12S39117,19.3
D13S31712,14
D16S53910
D18S5120
D19S43312.2,14
D21S1130,31
FGA18
Penta E5,16
TH016,7
TPOX9
vWA17

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Cross-references
Cell line databases/resources CCRID; 3111C0001CCC000745
Other Wikidata; Q94102686
Entry history
Entry creation06-Sep-2019
Last entry update20-May-2021
Version number5