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Cellosaurus MDA-MB-231sci (CVCL_XE60)

[Text version]

Cell line name MDA-MB-231sci
Accession CVCL_XE60
Resource Identification Initiative To cite this cell line use: MDA-MB-231sci (RRID:CVCL_XE60)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C200955.
Characteristics: Highly metastatic.
Sequence variations Heterozygous for BRAF p.Gly464Val (c.1391G>T) (ClinVar=VCV000040364) (from parent cell line).
Homozygous for CDKN2A deletion (from parent cell line).
Heterozygous for KRAS p.Gly13Asp (c.38G>A) (ClinVar=VCV000012580) (from parent cell line).
TERT c.228C>T (-124C>T); in promoter (from parent cell line).
Homozygous for TP53 p.Arg280Lys (c.839G>A) (ClinVar=VCV000376657) (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0062 (MDA-MB-231)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=1813

Liu L., Yao M., Kong H.-W., Zhu Y.-X., Wang X.-M., Zhao F.-Y., Yan M.-X.
High metastasis human breast carcinoma cell subline and establishing method thereof.
Patent number CN102071168A, 25-May-2011

Cell line databases/resources CCRID; 3142C0001000000712
Other Wikidata; Q95987394
Entry history
Entry creation06-Sep-2019
Last entry update02-Jul-2020
Version number2