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Cellosaurus Huh-7/M8 (CVCL_XE85)

[Text version]
Cell line name Huh-7/M8
Accession CVCL_XE85
Resource Identification Initiative To cite this cell line use: Huh-7/M8 (RRID:CVCL_XE85)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2014247.
Population: Japanese.
Characteristics: Highly metastatic.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6307; KDR; Simple; p.Gln472His (c.1416A>T); ClinVar=VCV000134603; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 20932; POLD3; Simple; p.Lys109Arg (c.326A>G) (p.Lys70Arg, c.209A>G); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0336 (Huh-7)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): Patent=CN105861442B

Markers:
AmelogeninX
CSF1PO11
D2S44112,14
D2S133819
D3S135815
D5S81812
D6S104313,15
D7S82011
D8S117914
D12S39120,21
D13S31710,11
D16S53910
D18S5115
D19S43313,14
D21S1130
FGA22,23
Penta D12
Penta E11
TH017
TPOX8,11
vWA16,18

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Publications

Patent=CN105861442B
Jiang D.-H., Chen B.-J., Xie H.-Y., Zhou L., Zheng S.-S.
High transfer hepatoma cell line and its construction method and application.
Patent number CN105861442B, 09-Jul-2019

Cross-references
Cell line databases/resources cancercelllines; CVCL_XE85
CCRID; 4201PAT-CCTCC00575
Encyclopedic resources Wikidata; Q94308768
Entry history
Entry creation06-Sep-2019
Last entry update05-Oct-2023
Version number11