ID   UTA6
AC   CVCL_XF79
SY   UTA 6
DR   Wikidata; Q98134398
RX   PubMed=7588596;
RX   PubMed=9484832;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 05-10-23; Version: 8
//
RX   PubMed=7588596; DOI=10.1002/j.1460-2075.1995.tb00148.x;
RA   Englert C., Hou X.-Y., Maheswaran S., Bennett P., Ngwu C., Re G.G.,
RA   Garvin A.J., Rosner M.R., Haber D.A.;
RT   "WT1 suppresses synthesis of the epidermal growth factor receptor and
RT   induces apoptosis.";
RL   EMBO J. 14:4662-4675(1995).
//
RX   PubMed=9484832; DOI=10.1038/sj.onc.1201558;
RA   Medema R.H., Klompmaker R., Smits V.A.J., Rijksen G.;
RT   "p21waf1 can block cells at two points in the cell cycle, but does not
RT   interfere with processive DNA-replication or stress-activated
RT   kinases.";
RL   Oncogene 16:431-441(1998).
//