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Cellosaurus NCCIT_CDDP (CVCL_XI44)

[Text version]

Cell line name NCCIT_CDDP
Accession CVCL_XI44
Resource Identification Initiative To cite this cell line use: NCCIT_CDDP (RRID:CVCL_XI44)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:27899; Cisplatin (CDDP).
Sequence variations Mutation; HGNC; 6844; MAP2K4; Simple; p.Lys309Asn (c.927G>C); Zygosity=Unspecified (from parent cell line).
Mutation; HGNC; 9588; PTEN; Simple; p.Arg173Pro (c.518G>C); ClinVar=VCV000185195; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Val272Cysfs*73 (c.814delG); Zygosity=Homozygous (from parent cell line).
Disease Testicular embryonal carcinoma (NCIt: C6341)
Non-central nervous system-localized embryonal carcinoma (ORDO: Orphanet_289362)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1451 (NCC-IT)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=31500094; DOI=10.3390/cancers11091316
Bakardjieva-Mihaylova V., Skvarova Kramarzova K., Slamova M., Svaton M., Rejlova K., Zaliova M., Dobiasova A., Fiser K., Stuchly J., Grega M., Rosova B., Zachoval R., Klezl P., Eis V., Kindlova E., Buchler T., Trka J., Boublikova L.
Molecular basis of cisplatin resistance in testicular germ cell tumors.
Cancers (Basel) 11:1316.1-1316.18(2019)

Cross-references
Other Wikidata; Q95992667
Entry history
Entry creation19-Dec-2019
Last entry update20-May-2021
Version number6