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Cellosaurus HaCaT A-5 (CVCL_XK16)

[Text version]

Cell line name HaCaT A-5
Synonyms HaCaT-ras clone A-5; HaCaT-ras A5; A-5; A5
Accession CVCL_XK16
Resource Identification Initiative To cite this cell line use: HaCaT A-5 (RRID:CVCL_XK16)
Comments Characteristics: Non-tumorigenic.
Transfected with: HGNC; 5173; HRAS.
Derived from sampling site: Back; skin; epidermis; keratinocyte.
Sequence variations Heterozygous for TP53 p.His179Tyr (c.535C>T) (ClinVar=VCV000127815) (from parent cell line).
Heterozygous for TP53 p.Arg282Trp (c.843_844CC>TT) (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Children:
CVCL_XK15 (HaCaT RT3)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line
Publications

PubMed=11583982; DOI=10.1016/S0002-9440(10)62541-2
Mueller M.M., Peter W., Mappes M., Huelsen A., Steinbauer H., Boukamp P., Vaccariello M., Garlick J., Fusenig N.E.
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
Am. J. Pathol. 159:1567-1579(2001)

PubMed=20097197; DOI=10.1016/j.yexcr.2010.01.020
Rasanen K., Vaheri A.
Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.
Exp. Cell Res. 316:1739-1747(2010)

Cross-references
Cell line collections CLS; 300494/p36431_HaCaT-ras_A5
Other Wikidata; Q93937678
Proteomic databases PRIDE; PXD013113
Entry history
Entry creation19-Dec-2019
Last entry update12-Jan-2021
Version number3