Home  |  Contact

Cellosaurus HaCaT40degree (CVCL_XK18)

[Text version]

Cell line name HaCaT40degree
Accession CVCL_XK18
Resource Identification Initiative To cite this cell line use: HaCaT40degree (RRID:CVCL_XK18)
Comments Characteristics: Adpated to grow at 40 Celsius.
Transfected with: HGNC; 5173; HRAS.
Derived from sampling site: Back; skin; epidermis; keratinocyte.
Sequence variations Heterozygous for TP53 p.His179Tyr (c.535C>T) (ClinVar=VCV000127815) (from parent cell line).
Heterozygous for TP53 p.Arg282Trp (c.843_844CC>TT) (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0038 (HaCaT)
Sex of cell Male
Age at sampling 62Y
Category Spontaneously immortalized cell line

PubMed=10523843; DOI=10.1038/sj.onc.1202934
Boukamp P., Popp S., Bleuel K., Tomakidi E., Burkle A., Fusenig N.E.
Tumorigenic conversion of immortal human skin keratinocytes (HaCaT) by elevated temperature.
Oncogene 18:5638-5645(1999)

PubMed=11583982; DOI=10.1016/S0002-9440(10)62541-2
Mueller M.M., Peter W., Mappes M., Huelsen A., Steinbauer H., Boukamp P., Vaccariello M., Garlick J., Fusenig N.E.
Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor.
Am. J. Pathol. 159:1567-1579(2001)

Other Wikidata; Q93937740
Entry history
Entry creation19-Dec-2019
Last entry update12-Jan-2021
Version number3