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Cellosaurus T24/MMC (CVCL_XX49)

[Text version]

Cell line name T24/MMC
Accession CVCL_XX49
Resource Identification Initiative To cite this cell line use: T24/MMC (RRID:CVCL_XX49)
Comments Population: Caucasian; Swedish.
Selected for resistance to: ChEBI; CHEBI:27504; Mitomycin C (MMC; MitC).
Derived from sampling site: Urinary bladder.
Sequence variations Mutation; HGNC; 5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0554 (T24)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

CLPUB00543
Min Q., Cao S.-N., Gan Y.-P., Song T.-S., Liu F.-X., Ning Z.-F.
Bladder cancer chemotherapy resistant cell harbors stem-like characteristics construction and characterization of T24 resistance strain of bladder cancer.
Clin. Oncol. J. 1:1004.09-1004.12(2019)

Cross-references
Other Wikidata; Q98133065
Entry history
Entry creation19-Dec-2019
Last entry update20-May-2021
Version number5