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Cellosaurus BxPC-3 human CLDN18.2 (CVCL_XZ31)

[Text version]
Cell line name BxPC-3 human CLDN18.2
Accession CVCL_XZ31
Resource Identification Initiative To cite this cell line use: BxPC-3 human CLDN18.2 (RRID:CVCL_XZ31)
Comments Population: Caucasian.
Doubling time: ~30 hours (KYinno=KC-1272).
Transfected with: HGNC; 2039; CLDN18 (isoform A2).
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 6770; SMAD4; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Val487_Pro492delinsAla (c.1460_1474delGTGTAGGTGCTGTCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; None_reported; -; Zygosity=- (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr220Cys (c.659A>G); ClinVar=VCV000127819; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0186 (BxPC-3)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) KYinno; KC-1272
Cell line databases/resources cancercelllines; CVCL_XZ31
Encyclopedic resources Wikidata; Q93433500
Entry history
Entry creation19-Dec-2019
Last entry update05-Oct-2023
Version number8