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Cellosaurus U2OS-tetR-PAmCherry1-KRAS G12D (CVCL_XZ89)

Cell line name U2OS-tetR-PAmCherry1-KRAS G12D
Accession CVCL_XZ89
Resource Identification Initiative To cite this cell line use: U2OS-tetR-PAmCherry1-KRAS G12D (RRID:CVCL_XZ89)
Comments Population: Caucasian.
Characteristics: The PAmCherry1 fluorescent protein is fused to the N-terminal of KRAS with p.Gly12Asp.
Transfected with: HGNC; 6407; KRAS (with p.Gly12Asp).
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein (with p.Glu31Val, p.Ala62Thr, p.Lys75Asn, p.Leu88Phe, p.Asn103Lys, p.Ser151Leu, p.Ile166Val, p.Gln168Pro, p.Leu170Val and p.Ile202Arg = PAmCherry1).
Miscellaneous: Cell line information from personal communication of Nan X.-L.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XZ88 (U2OS-tetR)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Cross-references
Encyclopedic resources Wikidata; Q98133790
Entry history
Entry creation19-Dec-2019
Last entry update05-Oct-2023
Version number8