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Cellosaurus AGS/EPI (CVCL_Y085)

[Text version]

Cell line name AGS/EPI
Accession CVCL_Y085
Resource Identification Initiative To cite this cell line use: AGS/EPI (RRID:CVCL_Y085)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI:47898; 4'-epidoxorubicin (Epirubicin).
Derived from sampling site: Stomach.
Sequence variations Mutation; HGNC; 2514; CTNNB1; Simple; p.Gly34Glu (c.101G>A); ClinVar=VCV000017584; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu453Lys (c.1357G>A); ClinVar=VCV000376470; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Ala (c.1634A>C); ClinVar=VCV000013659; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0139 (AGS)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=25169536; DOI=10.7314/APJCP.2014.15.16.6849
Felipe A.V., Moraes A.A., de Oliveira J., da Silva T.D., Forones N.M.
Establishment and partial characterization of an epirubicin-resistant gastric cancer cell line with upregulated ABCB1.
Asian Pac. J. Cancer Prev. 15:6849-6853(2014)

Cross-references
Other Wikidata; Q54748717
Entry history
Entry creation07-Nov-2014
Last entry update20-May-2021
Version number9