ID   U937/clone21
AC   CVCL_Y170
DR   CGH-DB; 9116-4
DR   Wikidata; Q54973779
RX   PubMed=14973057;
CC   Selected for resistance to: ChEBI; CHEBI:4911; Etoposide (VP-16).
CC   Sequence variation: PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
CC   Sequence variation: Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
CC   Sequence variation: Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
CC   Derived from sampling site: Pleural effusion.
DI   NCIt; C8263; Adult acute monocytic leukemia
DI   ORDO; Orphanet_514; Acute monoblastic/monocytic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_0007 ! U-937
SX   Male
AG   37Y
CA   Cancer cell line
DT   Created: 07-11-14; Last updated: 02-07-20; Version: 7
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RX   PubMed=14973057; DOI=10.1158/0008-5472.CAN-3263-2;
RA   Yasui K., Mihara S., Zhao C., Okamoto H., Saito-Ohara F., Tomida A.,
RA   Funato T., Yokomizo A., Naito S., Imoto I., Tsuruo T., Inazawa J.;
RT   "Alteration in copy numbers of genes as a mechanism for acquired drug
RT   resistance.";
RL   Cancer Res. 64:1403-1410(2004).
//