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Cellosaurus U937/UK110 (CVCL_Y174)

[Text version]

Cell line name U937/UK110
Synonyms UK110
Accession CVCL_Y174
Resource Identification Initiative To cite this cell line use: U937/UK110 (RRID:CVCL_Y174)
Comments Derived from sampling site: Pleural effusion.
Sequence variations PICALM-MLLT10 (CALM-AF10) gene fusion (from parent cell line).
Hemizygous for PTEN p.Gly129fs*51 (c.387_388insCGCC) (from parent cell line).
Homozygous for TP53 c.559+1G>A (p.Val173Trpfs*59); splice donor mutation (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0007 (U-937)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line
Publications

PubMed=8845304
Noguchi K., Naito M., Kataoka S., Yonehara S., Tsuruo T.
A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis.
Cell Growth Differ. 6:1271-1277(1995)

Cross-references
Other Wikidata; Q54973785
Entry history
Entry creation07-Nov-2014
Last entry update02-Jul-2020
Version number6