ID   H273
AC   CVCL_Y296
DR   BTO; BTO:0005140
DR   cancercelllines; CVCL_Y296
DR   Wikidata; Q54872038
RX   PubMed=19382257;
CC   Population: Caucasian.
CC   Karyotypic information: Has lost chromosome Y (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Transfected with: HGNC; 11998; TP53 (with p.Arg273His).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
DI   NCIt; C4450; Lung large cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0060 ! NCI-H1299
SX   Male
AG   43Y
CA   Cancer cell line
DT   Created: 07-11-14; Last updated: 05-10-23; Version: 13
//
RX   PubMed=19382257; DOI=10.1002/jmv.21486;
RA   Nasirudeen A.M.A., Liu D.-X.;
RT   "Gene expression profiling by microarray analysis reveals an important
RT   role for caspase-1 in dengue virus-induced p53-mediated apoptosis.";
RL   J. Med. Virol. 81:1069-1081(2009).
//