ID   L1210/DACH
AC   CVCL_Y419
SY   L1210(DACH); L1210 (DACH); L1210DACH
DR   ChEMBL-Cells; CHEMBL3308408
DR   ChEMBL-Targets; CHEMBL614041
DR   PubChem_Cell_line; CVCL_Y419
DR   Wikidata; Q54900958
RX   PubMed=1986276;
RX   PubMed=3335002;
RX   PubMed=3828995;
RX   PubMed=6541096;
CC   Selected for resistance to: ChEBI; CHEBI:90269; Dichloro(1,2-diaminocyclohexane)platinum(II) (DACHPt).
CC   Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: DBA/2.
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_Y418 ! L1210/0
SX   Female
AG   8M
CA   Cancer cell line
DT   Created: 07-11-14; Last updated: 05-10-23; Version: 14
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RX   PubMed=1986276; DOI=10.1016/0921-8777(91)90044-P;
RA   Jennerwein M.M., Eastman A., Khokhar A.R.;
RT   "The role of DNA repair in resistance of L1210 cells to isomeric
RT   1,2-diaminocyclohexaneplatinum complexes and ultraviolet
RT   irradiation.";
RL   Mutat. Res. 254:89-96(1991).
//
RX   PubMed=3335002;
RA   Kraker A.J., Moore C.W.;
RT   "Accumulation of cis-diamminedichloroplatinum(II) and platinum
RT   analogues by platinum-resistant murine leukemia cells in vitro.";
RL   Cancer Res. 48:9-13(1988).
//
RX   PubMed=3828995;
RA   Richon V.M., Schulte N., Eastman A.;
RT   "Multiple mechanisms of resistance to cis-diamminedichloroplatinum(II)
RT   in murine leukemia L1210 cells.";
RL   Cancer Res. 47:2056-2061(1987).
//
RX   PubMed=6541096;
RA   Eastman A., Illenye S.;
RT   "Murine leukemia L1210 cell lines with different patterns of
RT   resistance to platinum coordination complexes.";
RL   Cancer Treat. Rep. 68:1189-1190(1984).
//