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Cellosaurus PGA-1 (CVCL_Y545)

[Text version]
Cell line name PGA-1
Synonyms PGA1; PG A1; CLL-PGA
Accession CVCL_Y545
Resource Identification Initiative To cite this cell line use: PGA-1 (RRID:CVCL_Y545)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: LL-100 blood cancer cell line panel.
Population: Caucasian.
Doubling time: ~50 hours (DSMZ=ACC-766).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by RNAseq.
HLA typing Source: DSMZCellDive=ACC-766
Class I
HLA-AA*02:01:01,03:01:01
HLA-BB*35:03:01,39:01:01
HLA-CC*07:02:01,12:03:01
Class II
HLA-DPDPA1*01:03:01,01:03:01
DPB1*04:02:01,02:01:02
HLA-DQDQA1*01:02:01,05:05:01
DQB1*03:01:01,06:09:01
HLA-DRDRA*01:02:02,01:02:02
DRB1*12:01:01,13:02:01
Disease Chronic lymphocytic leukemia (NCIt: C3163)
B-cell chronic lymphocytic leukemia (ORDO: Orphanet_67038)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_Y555 ! PG/B95-8
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap; DSMZ

Markers:
AmelogeninX,Y
CSF1PO13
D2S133817,18
D3S135815,16
D5S81811,12
D7S82010,11
D8S117913
D13S3178,12
D16S53912
D18S5115
D19S43314,15
D21S1128,30
FGA20,22
Penta D9,14
Penta E12
TH016,9.3
TPOX8,11
vWA17

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Publications

PubMed=2836321; DOI=10.1002/ijc.2910410621
Lewin N., Aman P., Mellstedt H., Zech L., Klein G.
Direct outgrowth of in vivo Epstein-Barr virus (EBV)-infected chronic lymphocytic leukemia (CLL) cells into permanent lines.
Int. J. Cancer 41:892-895(1988)

PubMed=23297799; DOI=10.3109/10428194.2013.764418
Myhrinder A.L., Hellqvist E., Bergh A.-C., Jansson M., Nilsson K., Hultman P., Jonasson J., Buhl A.M., Pedersen L.B., Jurlander J., Klein E., Weit N., Herling M., Rosenquist R., Rosen A.
Molecular characterization of neoplastic and normal 'sister' lymphoblastoid B-cell lines from chronic lymphocytic leukemia.
Leuk. Lymphoma 54:1769-1779(2013)

PubMed=31160637; DOI=10.1038/s41598-019-44491-x
Quentmeier H., Pommerenke C., Dirks W.G., Eberth S., Koeppel M., MacLeod R.A.F., Nagel S., Steube K., Uphoff C.C., Drexler H.G.
The LL-100 panel: 100 cell lines for blood cancer studies.
Sci. Rep. 9:8218-8218(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-766
NCBI_Iran; C583
Cell line databases/resources cancercelllines; CVCL_Y545
Cell_Model_Passport; SIDM01855
DepMap; ACH-001634
DSMZCellDive; ACC-766
Encyclopedic resources Wikidata; Q54947324
Gene expression databases ArrayExpress; E-MTAB-7721
ArrayExpress; E-MTAB-7722
Entry history
Entry creation07-Nov-2014
Last entry update05-Oct-2023
Version number13