| Cell line name |
HSC3/hPDPN |
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| Synonyms |
HSC3-hPDPN |
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| Accession |
CVCL_YA14 |
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| Resource Identification Initiative |
To cite this cell line use: HSC3/hPDPN (RRID:CVCL_YA14) |
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| Comments |
Population: Japanese.
Transfected with: HGNC; 29602; PDPN.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429. |
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| Sequence variations |
- Mutation; HGNC; 1787; CDKN2A; Simple; p.Glu120Ter (c.358G>T); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Gly (c.1634A>G); ClinVar=VCV000013656; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Lys305fs (c.912_913insTAAG); Zygosity=Unspecified (from parent cell line).
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| Disease |
Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1288 (HSC-3) |
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| Sex of cell |
Male |
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| Age at sampling |
64Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=23012488; DOI=10.1267/ahc.12008
Kaji C., Tsujimoto Y., Kaneko M.K., Kato Y., Sawa Y.
Immunohistochemical examination of novel rat monoclonal antibodies against mouse and human podoplanin.
Acta Histochem. Cytochem. 45:227-237(2012) PubMed=25080943; DOI=10.1038/srep05924
Kato Y., Kaneko M.K.
A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin.
Sci. Rep. 4:5924-5924(2014) PubMed=28387591; DOI=10.1089/mab.2017.0001
Yamada S., Ogasawara S., Kaneko M.K., Kato Y.
LpMab-23: a cancer-specific monoclonal antibody against human podoplanin.
Monoclon. Antib. Immunodiagn. Immunother. 36:72-76(2017) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q94302977
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| Entry history |
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| Entry creation | 19-Dec-2019 |
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| Last entry update | 30-Jan-2024 |
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| Version number | 9 |
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